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ETUDES Center 1.0

The Center for Enhancing Treatment and Utilization for Depression and Emergent Suicidality (ETUDES) in Pediatric Primary Care (ETUDES Center)

NIH Reporter

Back to Dr. Brent's Research

Dates: 7/17/2018-4/30/2022

Background

Suicide was the second leading cause of death among adolescents and had increased by 20% over the past decade. Most teens who died by suicide had their last medical visit in a primary care setting. This research center carried out three studies to help pediatric primary care providers (PCPs) better identify, manage, and support teens who were depressed or suicidal.

Study 1: Decision Support System (DSS)

  • We created a digital decision support system to guide PCPs in making treatment recommendations.
  • The system considered how severe the teen’s symptoms were, as well as barriers, attitudes, and treatment preferences.
  • This helped PCPs follow best practices when teens screened positive for depression or suicidal thoughts.

Study 2: Personalized Texting Intervention

  • We developed and tested a texting program to improve attendance at treatment appointments.
  • The messages were personalized to address motivation, readiness, and barriers for both teens and their parents.
  • This approach aimed to increase the low rate of follow-through after a positive depression screen.

Study 3: Safety Planning App

  • We built and tested an app to guide PCPs when a teen was found to be suicidal during routine screening.
  • The app helped create a safety plan and stabilize the teen, reducing unnecessary emergency room visits and hospitalizations.

These studies used technology to personalize care based on each teen’s needs and situation. They were expected to make a big impact by improving treatment attendance and reducing suicide attempts among high-risk teens.

Primary Selected Outcome Papers:

  1. PMC - The Child and Adolescent Services Assessment: Interrater Reliability and Predictors of Rater Disagreement
  2. PubMed - Commentary: Reducing Adolescent Suicide: A Global Imperative - A Reflection on Glenn, et al.
  3. PubMed - Bridging Gaps in Follow-Up Appointments After Hospitalization and Youth Suicide: Mental Health Care Dispartities Matter
  4. PubMed - Phonotype: A New Taxonomy for mHealth Research
  5. PubMed - Social Media Use and Deliberate Self-Harm Among Youth: A Systematized Narrative Review
  6. PubMed - Affective Dynamics Across Internalizing and Externalizing Dimensions of Psychopathology
  7. PubMed - Brief Behavioral Therapy for Pediatric Anxiety and Depression in Primary Care: A Follow-Up
  8. PubMed - Social Media Use and Monitoring for Adolescents with Depression and Implications for the COVID-19 Pandemic: Qualitative Study Parent and Child Perspectives
  9. PMC - Digital Approaches to Remote Pediatric Health Care Delivery During the COVID-19 Pandemic: Existing Evidence and a Call for Further Research
  10. PubMed - Effects of primary Care Provider Characteristics on Changes in Behavioral Health Delivery During a Collaborative Care Trial
  11. PubMed - Regulators, Payors, and the Impact of Measurement-Based Care on Value-Based Care in Psychiatry
  12. PubMed - Risk and Protective Factors for Childhood Suicidality: A US Population-Based Study
  13. MDPI - Adolescent Perspectives on How an Adjunctive Mobile App for Social Anxiety Treatment Impacts Treatment Engagement in Telehealth Group Therapy
  14. PubMed - Stakeholder Perspectives on Digital Behavioral Health Applications Targeting Adolescent Depression and Suicidality: Policymaker, Provider, and Community Insights
  15. Hapres - Sleep Health Disparities: Promising Target for Preventing Suicide in Black Youth?
  16. PubMed - Classifying Social Determinants of Health from Unstructured Electronic Health Records Using Deep Learning-Based Natural Language Processing
  17. PubMed - Centering Lived Experience in Developing Digital Interventions for Suicide and Self-Injurious Behaviors: User-Centered Design Approach
  18. PubMed - A Text Message Intervention for Adolescents with Depression and Their Parents or Caregivers to Overcome Cognitive Barriers to Mental Health Treatment Initiation: Focus Groups and Pilot Trial
  19. PubMed - Acceptability, Engagement, and Effects of a Mobile Digital Intervention to Support Mental Health for Young Adults Transitioning to College: Pilot Randomized Controlled Trial
  20. PubMed - Automated Monitoring of Suicidal Adolescents' Digital Media Use: Qualitative Study Exploring Acceptability Within Clinical Care
  21. PubMed - Perceived Facilitators of and Barriers to Implementation of a Decision Support Tool for Adolescent Depression and Suicidality Screening: Focus Group and Interview Study
  22. PubMed - Natural Language Processing and Machine Learning of Electronic Health Records for Prediction of First-Time Suicide Attempts
  23. PubMed - Extending Our Virtual Reach: Pediatricians and Mental Health Providers Bridging the Chasm to Mental Health Care for Adolescents and Transition-Age Youth During COVID-19
  24. PMC - The Elusive Phenotype of Preadolescent Suicidal Thoughts and Behaviors: Can Neuroimaging Deliver on Its Promise?
  25. PubMed - Support-Seeking Over Social Media Among Rural SGM Youth: Opportunities for Intervention Research
  26. Frontiers - Exploring Technology-Based Alternatives for Combating Social Isolation: Online Interviews with Rural Sexual and Gender Minority Youth
  27. PubMed - Adolescent Depression Screening in Primary Care: Who is Screened and Who is at Risk?
  28. PubMed - Support Over Social Media Among Socially Isolated Sexual and Gender Minority Youth in Rural US During the COVID-19 Pandemic: Opportunities for Intervention Research
  29. PubMed - A Comprehensive Review of the Literature on Sleep Difficulties and Suicidality in Youth to Inform an Integrative Developmental Model and Future Directions
  30. PubMed - Predicting Depression in Adolescents Using Mobile and Wearable Sensors: Multimodal Machine Learning-Based Exploratory Study
  31. PubMed - Development of an Ecological Momentary Assessment of the Impact of Social Media Use Among Suicidal Adolescents
  32. PubMed - A Protocol for Applying Health Equity-Informed Implementation Science Models and Frameworks to Adapt a Sleep Intervention for Adolescents at Risk for Suicidal Thoughts and Behaviors
  33. PubMed - Responding to the Opioid Crisis in North America and Beyond: Recommendations of the Standford-Lancet Commission